Combined dataset of Rodent Gambling Task in rats after brain injury

DOI:10.34945/F5Q597

DATASET CITATION

Vonder Haar C., Martens K. M., Frankot M. A. (2022) Combined dataset of Rodent Gambling Task in rats after brain injury. ODC-TBI:703 http://doi.org/10.34945/F5Q597

ABSTRACT

STUDY PURPOSE: The goal of this analysis set was to compare data collected across four separate studies, all of which evaluated the effects of traumatic brain injury on the Rodent Gambling Task (RGT). This combined data would have sufficient power to analyze both overall and trial-by-trial outcomes.

DATA COLLECTED: Data were collected across four studies comprising training and testing on the RGT. Three studies were bilateral frontal controlled cortical impact injuries and one was unilateral, parietal controlled cortical impact. Two trained rats before injury, and two after. A total of 109 rats in TBI or Sham conditions (no other manipulations) can be extracted from these data. Two of these studies are published, one is in review, and one is in preparation for publication.

CONCLUSIONS: Our key finding from the manuscript was that theoretical approaches (sensitivity to overall outcomes vs. sensitivity to immediate outcomes) was less effective at accounting for data than an unbiased k-means clustering approach. The clustering readily identified different phenotypes of decision-making on this task and TBI rats were less likely to be in the "optimal" category and instead were evenly spread across all other categories. The current findings suggest that TBI does not engender a "risky" decision-making trait per se, but rather fundamentally changes the preference for outcomes of rats with injury.

KEYWORDS

Traumatic brain injury; Decision making; rat; phenotype; Impulsivity

PROVENANCE / ORIGINATING PUBLICATIONS

• Unilateral parietal brain injury increases risk-taking on a rat gambling task.. doi:10.1016/j.expneurol.2020.113217.

One of the four datasets included in this (CCI-E identifier).

• Long-term deficits in risky decision-making after traumatic brain injury on a rat analog of the Iowa gambling task. doi:10.1016/j.brainres.2018.10.004.

One of the four datasets included in this analysis (CCI-A identifier).

RELEVANT LINKS

NOTES

DATASET INFO

Contact: Vonder Haar Cole (cole.vonderhaar@osumc.edu)

Lab: Vonder Haar Lab

ODC-TBI Accession:703

Records in Dataset: 684927

Fields per Record: 38

Last updated: 2022-03-19

Date published: 2022-03-19

Downloads: 40

Files: 3

LICENSE

Creative Commons Attribution License (CC-BY 4.0)

FUNDING AND ACKNOWLEDGEMENTS

National Institutes of Health grants R01-NS1109 (CV and KMM), P20-GM103434 (CV), U54-GM104942

CONTRIBUTORS

Vonder Haar, Cole

Injury and Recovery Laboratory, Department of Neuroscience, Ohio State University, Columbus, OH, USA; Electronic address: cole.vonderhaar@osumc.edu

Martens, Kris M.

Injury and Recovery Laboratory, Department of Neuroscience, Ohio State University, Columbus, OH, USA.

Ozga-Hess, Jenny E.

Injury and Recovery Laboratory, Department of Psychology, West Virginia University, Morgantown, WV, USA.

Frankot, Michelle A.

Injury and Recovery Laboratory, Department of Psychology, West Virginia University, Morgantown, WV, USA

Pechacek, Kristen

Injury and Recovery Laboratory, Department of Psychology, West Virginia University, Morgantown, WV, USA.

Shaver, Trinity K.

Injury and Recovery Laboratory, Department of Psychology, West Virginia University, Morgantown, WV, USA.

O'Hearn, Christopher

Injury and Recovery Laboratory, Department of Psychology, West Virginia University, Morgantown, WV, USA.

Whirtley, Cory

Injury and Recovery Laboratory, Department of Psychology, West Virginia University, Morgantown, WV, USA.

Zhu, Binxing

Injury and Recovery Laboratory, Department of Psychology, West Virginia University, Morgantown, WV, USA.

Blancke, Alyssa M.

Injury and Recovery Laboratory, Department of Psychology, West Virginia University, Morgantown, WV, USA

Rodriguez, Bryan

Injury and Recovery Laboratory, Department of Psychology, West Virginia University, Morgantown, WV, USA